Cardiac contractility and oxygen consumption.
نویسندگان
چکیده
منابع مشابه
Perfusion-induced changes in cardiac contractility and oxygen consumption are not endothelium-dependent.
OBJECTIVE Are substances released from rat coronary endothelial cells responsible for the increase in contractility and oxygen consumption (Gregg phenomenon) seen with an increase in cardiac perfusion? METHODS In an isovolumically contracting, Langendorff, crystalloid perfused rat heart (n = 6) at 27 degrees C, coronary flow was changed (from 4.4 to 15.4 ml.min-1.gww(-1)) before and after the...
متن کاملNitric oxide modulates cardiac contractility and oxygen consumption without changing contractile efficiency.
Nitric oxide (NO) affects myocardial contractility and myocardial oxygen consumption (MV˙o 2) in vitro. In α-chloralose-anesthetized dogs instrumented for the measurements of left ventricular (LV) pressure, LV volume using a conductance catheter, coronary blood flow, and coronary venous oxygen saturation (S[Formula: see text]) using a fiber-optic catheter, LV end-systolic pressure-volume relati...
متن کاملProgressive hypoxemia limits left ventricular oxygen consumption and contractility.
To study the cardiac effects of progressive hypoxemia, we measured the left ventricular end-systolic pressure-volume relation (ESPVR), myocardial oxygen consumption (MVO2), and myocardial oxygen delivery (MQO2) in eight thoracotomized dogs anesthetized with fentanyl and droperidol. We specifically looked for evidence of oxygen supply limitation of MVO2 and depressed contractility (altered ESPVR...
متن کاملCardiac work and contractility.
It has been customary to regard the heart as a pump maintaining the flow of blood, and to assess the work done by the heart from the pressure and volume of blood leaving the ventricles. While correct in physical terms, measurement of external cardiac work in this way is a poor index of the myocardial oxygen consumption which is related to the work done by the ventricular muscle. Systolic pressu...
متن کاملInfluence of Coronary Flow upon Oxygen Consumption and Cardiac Performance.
• Work of our department and of others has shown that the magnitude of coronary flow (CF) is determined primarily by the oxygen consumption of the heart (OoC)" in such a manner that oxygen availability alters in a parallel fashion with O2C while oxygen extraction (O2E), within limits, remains constant." Two kinds of factors cause deviation of this relationship : (A) Factors which independently ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA
سال: 1988
ISSN: 0285-4945,1349-9149
DOI: 10.2199/jjsca.8.1